Company Profile
Novartis researches, develops, manufactures, distributes, markets, and sells pharmaceutical medicines in Switzerland and globally. The company offers Entresto, an angiotensin receptorneprilysin inhibitor to treat symptomatic chronic heart failure with reduced ejection fraction (HFrEF).
Its portfolio also includes Cosentyx to treat plaque psoriasis, pso riatic arthritis, ankylosing spondylitis, and nonradiographic axial spondy loarthritis, Kisqali, a selective oral cyclin dependent inhibitor of kinases 4 and 6 (CDK4/6), Promacta/Revolade to treat immune thrombocytopenia (ITP), thrombocytopenia, and patients with severe aplastic anemia (SAA), Tafinlar+Mekinist, an oral combination therapy to treat patients with certain types of cancers, and Jakavi for the treatment of myelofibrosis, polycythemia vera, and acute or chronic graftversushost disease (GvHD), as well as Tasigna to treat philadelphia chromosomepositive chronic myeloid leukemia in the chronic and/or accelerated phase.
Its portfolio also includes Xolair for the treatment of allergic asthma and nasal polyps or severe chronic rhinosi nusitis with nasal polyps, Ilaris to treat fever syndromes, Still's disease, and acute gouty arthritis, Pluvicto to treat prostatespecific membrane anti genpositive metastatic castrationresistant prostate cancer, Sandostatin SC and Sandostatin LAR to treat acromegaly carcinoid tumors and types of functional gastro intestinal and pancreatic neuroendocrine tumors, Zolgensma for the treatment of genetic root cause of spinal muscular atrophy, Lucentis, Leqvio to reduce LDL cholesterol, Lutathera, Scemblix, and Fabhalta.
The company focuses on therapeutic areas, such as cardiovascular, renal and metabolic, immunology, neuroscience, oncology, and hematology. It has a license and collaboration agreement with Alnylam Pharmaceuticals, Inc. to develop, manufacture, and commercialize Leqvio (inclisiran), a therapy to reduce LDL cholesterol. Incorporated in 1996, Novartis is headquartered in Basel, Switzerland.