Pacific Biosciences of California designs, develops, and manufactures sequencing solutions to resolve genetically complex problems. The company provides sequencing systems. Its portfolio also includes consumable products, including single molecule real-time (SMRT) technology, long-read sequencing, and various reagent kits designed for specific workflow, such as preparation kit to convert DNA into SMRTbell double-stranded DNA library formats
Including molecular biology reagents, such as ligase, buffers, and exonucleases, as well as binding kits, such as modified DNA polymerase used to bind SMRTbell libraries to the polymerase in preparation for sequencing
Sequencing kits comprise reagents required for on-instrument, real-time sequencing, including the phospholinked nucleotides. Additionally, it provides Revio, Vega, and Sequel instruments which conduct, monitor, and analyze single-molecule biochemical reactions on SMRT cell microchips.
Its portfolio also includes short-read sequencing, and onso instrument. The company serves academic and governmental research institutions, commercial testing and service laboratories, genome centers, public health labs, hospitals and clinical research institutes, contract research organizations, pharmaceutical companies, and agricultural companies.
The company markets its products through a sales force and distribution partners in Australia, certain parts of Asia, Europe, the Middle East, Africa, Central America, and South America. It has a collaboration with DNAstack Inc. to provide federated dataset of HiFi whole genome sequencing data. Incorporated in 2000 and headquartered in Menlo Park, California, Pacific Biosciences of California was formerly known as Nanofluidics, Inc. before rebranding in 2005.